ProDen PlaqueOff Dental Care Bones are dog chews with the proven PlaqueOff Powder as one of the ingredients. Used daily, this natural product made with kelp can significantly complement ordinary dental hygiene. Dogs constantly produce new plaque in their mouths. Untreated, this can calcify into tartar which cannot be brushed away. A vet needs to remove tartar with anesthesia and ultrasound. Untreated tartar can lead to infections which can damage the heart, lungs, liver and adversely affect renal function. ProDen offers effective and simple options for your pet's dental and oral hygiene.